acd logp software package version 4.55 (ACD Labs Inc)
90
Structured Review
ACD Labs Inc
acd logp software package version 4.55
Acd Logp Software Package Version 4.55, supplied by ACD Labs Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/acd+logp+software+package+version+4%2E55/acd+logp+software+package+version+4+55/pm36768301-360-8-14
Average 90 stars, based on 1 article reviews
Acd Logp Software Package Version 4.55, supplied by ACD Labs Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/acd+logp+software+package+version+4%2E55/acd+logp+software+package+version+4+55/pm36768301-360-8-14
Average 90 stars, based on 1 article reviews
acd logp software package version 4.55 - by Bioz Stars,
2026-09
90/100 stars
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Software:Article Title: Carvacrol prodrugs as novel antimicrobial agents. Article Snippet: Carvacrol prodrugs As novel antimicrobial agents Article Title: A Novel Prodrug of a nNOS Inhibitor with Improved Pharmacokinetic Potential Article Snippet: The cLogP values were calculated using the ACD Article Title: Codrugs linking L-dopa and sulfur-containing antioxidants: new pharmacological tools against Parkinson's disease. Article Snippet: A series of multifunctional codrugs (1-6) were synthesized to overcome the pro-oxidant effect associated with L-dopa (LD) therapy.. Target compounds release LD and dopamine (DA) in human plasma after enzymatic hydrolysis, displaying an antioxidant effect superior to that of N-acetylcysteine (NAC).. After intracerebroventricular injection of codrug 4, the levels of DA in the striatum were higher than those in LD-treated groups, indicating that this compound has a longer half-life in brain than LD. Article Title: Resveratrol Derivative Exhibits Marked Antiproliferative Actions, Affecting Stemness in Pancreatic Cancer Cells. Article Snippet: The calculated LogP (cLogP) value was determined using ACD Article Title: Ibuprofen and lipoic acid diamides as potential codrugs with neuroprotective activity. Article Snippet: Current evidences support the hypothesis that non-steroidal anti-inflammatory drugs (NSAIDs) and antioxidant therapy might protect against the development of Alzheimer’s disease (AD).. In the present work, our attention was focused on ibuprofen (IBU) used in clinical trails to prevent Alzheimer’s disease, and (R)-a-lipoic acid (LA) considered as a potential neuroprotective agent in AD therapy.. In particular, we investigated a series of lipophilic molecular combinations obtained by joining (R)-a-lipoic acid and ibuprofen via an amide bond. Article Title: Synthesis and Biological Evaluation of Novel Selenyl and Sulfur- l -Dopa Derivatives as Potential Anti-Parkinson’s Disease Agents Article Snippet: The cl ogP values were calculated using ACD Article Title: Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease. Article Snippet: Non-steroidal anti-inflammatory drugs (NSAIDs) and antioxidant therapy might protect against the development of Alzheimer’s disease (AD).. In the present work, we synthesized a molecular combination of glutathione (GSH) and ibuprofen (IBU) via an amide bond and investigated its potential for targeted delivery of the parent drugs to neurons, where cellular oxidative stress and inflammation are related to AD.. Evaluation of its physicochemical and in-vitro antioxidant properties indicated that compound 1 exhibits good stability toward human plasma enzymatic activity, and, like GSH, displays in-vitro free radical scavenging activity in a time and concentration-dependent manner. Concentration Assay:Article Title: Carvacrol prodrugs as novel antimicrobial agents. Article Snippet: Carvacrol prodrugs As novel antimicrobial agents Article Title: A Novel Prodrug of a nNOS Inhibitor with Improved Pharmacokinetic Potential Article Snippet: The cLogP values were calculated using the ACD Article Title: Codrugs linking L-dopa and sulfur-containing antioxidants: new pharmacological tools against Parkinson's disease. Article Snippet: A series of multifunctional codrugs (1-6) were synthesized to overcome the pro-oxidant effect associated with L-dopa (LD) therapy.. Target compounds release LD and dopamine (DA) in human plasma after enzymatic hydrolysis, displaying an antioxidant effect superior to that of N-acetylcysteine (NAC).. After intracerebroventricular injection of codrug 4, the levels of DA in the striatum were higher than those in LD-treated groups, indicating that this compound has a longer half-life in brain than LD. Article Title: Resveratrol Derivative Exhibits Marked Antiproliferative Actions, Affecting Stemness in Pancreatic Cancer Cells. Article Snippet: The calculated LogP (cLogP) value was determined using ACD Article Title: Ibuprofen and lipoic acid diamides as potential codrugs with neuroprotective activity. Article Snippet: Current evidences support the hypothesis that non-steroidal anti-inflammatory drugs (NSAIDs) and antioxidant therapy might protect against the development of Alzheimer’s disease (AD).. In the present work, our attention was focused on ibuprofen (IBU) used in clinical trails to prevent Alzheimer’s disease, and (R)-a-lipoic acid (LA) considered as a potential neuroprotective agent in AD therapy.. In particular, we investigated a series of lipophilic molecular combinations obtained by joining (R)-a-lipoic acid and ibuprofen via an amide bond. Article Title: Synthesis and Biological Evaluation of Novel Selenyl and Sulfur- l -Dopa Derivatives as Potential Anti-Parkinson’s Disease Agents Article Snippet: The cl ogP values were calculated using ACD Article Title: Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease. Article Snippet: Non-steroidal anti-inflammatory drugs (NSAIDs) and antioxidant therapy might protect against the development of Alzheimer’s disease (AD).. In the present work, we synthesized a molecular combination of glutathione (GSH) and ibuprofen (IBU) via an amide bond and investigated its potential for targeted delivery of the parent drugs to neurons, where cellular oxidative stress and inflammation are related to AD.. Evaluation of its physicochemical and in-vitro antioxidant properties indicated that compound 1 exhibits good stability toward human plasma enzymatic activity, and, like GSH, displays in-vitro free radical scavenging activity in a time and concentration-dependent manner. |